TotalMarketCap

Spyre Therapeutics

SYRENasdaq United StatesHealth CareBiotechnology: Pharmaceutical Preparations

Market cap

$9.206 B

$96.94 -2.12%

Close of 6 Nov 2026

As of 6 Nov 2026, Spyre Therapeutics (SYRE) has a market capitalization of $9.21B. Market cap measures the value of outstanding equity at market prices; company totals combine applicable share classes. Prices and market caps come from Nasdaq, with financial fundamentals from SEC filings. See sources and calculation details.

Revenue

$0.00

#3616 by revenue

Earnings

-$155.2M

Loss-making

Shares outstanding

94,969,184

Latest filing cover page

P/E ratio

—

Cap ÷ net income

Biotechnology: Pharmaceutical Preparations, ranked by market cap

All 498 →
  1. #32Biomarin PharmaceuticalBMRN$10.9B
  2. #33Madrigal PharmaceuticalsMDGL$9.30B
  3. #34Spyre TherapeuticsSYRE$9.21B
  4. #35Tg TherapeuticsTGTX$8.87B
  5. #36Protagonist TherapeuticsPTGX$8.76B

What if Spyre Therapeutics were worth as much as…

Open the what-if tool →

Gold $28.2T

$297,326.70

Per share 3,067× higher

Bitcoin $1.53T

$16,087.83

Per share 166× higher

Apple $5.02T

$52,814.84

Per share 545× higher

Or at a round number

$20.0B$50.0B$100.0B$200.0B

Where these numbers come from

Share counts and financials for Spyre Therapeutics are taken from its own SEC filings via EDGAR: public record, not an estimate. Market cap is shares outstanding multiplied by the latest close. Read the methodology.